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Pinch to Zoom Beta Blocker
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Bradley Cooper or Brad Pitt
What happens to your heart and lungs if you met them?
Brad has one heart and two lungs
What happens to your heart and lungs if you met them?
Brad has one heart and two lungs
Seeing Bradley increases the heart rate
Blocking Bradley decreases the heart rate
Brad has 1 heart, 1 pair of kidneys, 2 lungs Beta 1 receptors located on heart and kidneys. Beta 2 receptors located on lungs
Push buttons to make the heart beat faster
Slow down the heart by blocking the heart receptors (beta receptors)
Treart abnormal heart rhythms
Beta receptors belong to sympathetic nervous system Felt sympathetic for Brad's breakup
Sympathetic nervous system (SNS) increases heart rate
SNS increases blood pressure
SNS increases heart contractions
SNS causes brondilation
SNS increases blood glucose
Epinephrine and norepinephrine work on beta receptors
Beta blockers block beta receptors
Beta 1 receptors found in heart
Beta 1 receptors found in kidneys
Beta 1 receptors increase heart work load Brad Pitt has one heart. Seeing Brad Pitt would make my heart race. If you block my view of Brad, my heart rate would decrease.
Beta blockers decrease renin release
Beta blockers widen blood vessels (vasodilation). The opposite is vasoconstriction.
Beta blocker less effective for high blood pressure than diuretics or RAAS meds
Blocked beta receptors indirectly reduces open L-type calcium channels
Blocked beta receptors impact the calcium entering at action potential phase 4
Decreases the SA node fire rate
Decreases conduction velocity in AV node
Beta blocker extends ECG PR interval
PR interval time between atrial depolarization and ventricle repolarization
Beta blockers treat supraventricular tachycardia
Supraventricular tachycardia includes atrial fibrillation and atrial flutter
*Beta 1 receptor locations, Beta 2 receptor locations, selective, non-selective
Adenylyl Cyclase
ATP
ATP
ATP
cAMP
cAMP
Beta 1
Heart, Kidney
Heart, Kidney
Beta blocker
Heart Rate, Receptors, Renin, Vasoconstriction
Heart Rate, Receptors, Renin, Vasoconstriction
cAMP
PK-A
PK-A
Enzyme
Adenylyl Cyclase
Adenylyl Cyclase
Kidney
Renin
Renin
PK-A
Calcium Channels
Calcium Channels
Receptors
Beta 1, Enzyme, Epinephrine, Norepinephrine
Beta 1, Enzyme, Epinephrine, Norepinephrine
Sympathetic Nervous System
Heart Rate
Heart Rate
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Which system do Beta blockers act on? Sympathetic
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Which neurotransmitter is blocked by beta blockers? Norepinephrine
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What is norepinephrine? Hormone
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What do beta blockers prevent? Vasoconstriction
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What do beta blockers do to the heart rate? Decrease Beta blockers block the receptors
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What do beta blockers do to heart muscle contraction? Decrease Beta blockers block the receptors
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Seeing Bradley increases the heart rate
Blocking Bradley decreases the heart rate
Brad has 1 heart, 1 pair of kidneys, 2 lungs
Beta 1 receptors located on heart and kidneys. Beta 2 receptors located on lungs
Push buttons to make the heart beat faster
Slow down the heart by blocking the heart receptors (beta receptors)
Seeing Bradley increases the heart rate
Blocking Bradley decreases the heart rate
Brad has 1 heart, 1 pair of kidneys, 2 lungs
Beta 1 receptors located on heart and kidneys. Beta 2 receptors located on lungsPush buttons to make the heart beat faster
Slow down the heart by blocking the heart receptors (beta receptors)