StudyGallery.com Statins

Do you know your cholesterol?

Bile salts contain high levels of cholesterol

The liver pulls cholesterol from the blood to make new bile acids

HMG-CoA is the enzyme blocked by statins

Bile acids break down fats

The liver processes fats to LDLs

HDLs help absorb fats

Cholesterol provides structure for the cell membrane

Lipoproteins are produced in the liver

*HDL, LDL, HMG-CoA

Cells
Cholesterol

Cholesterol
Bile Acids

Fats
LDL

HMG-CoA inhibitors
LDL, Statins

Liver
Fats

What contains high levels of cholesterol? Bile Salts

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Where will the liver pull cholesterol to make new bile acids? Blood

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What do statins block? Enzyme

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What is the enzyme blocked by statins? HMG-CoA

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What is used to break down fats? Bile Acids

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Which tissue stores fat? Adipose Tissue

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Where are fats processed to LDLs? Liver

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What does cholesterol help make? Bile Acids

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What do HDLs help absorb? Fats

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What does cholesterol provide structure for? Cell Membrane

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Where are lipoproteins produced? Liver

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What is HMG-CoA? Enzyme

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Which cells is HMG-CoA active? All

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What do bile acid sequestrants prevent bile acids from? Reabsorption

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What do bile sequestrants prevent reabsorption of? Bile Acids

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What happens to LDL levels when HMG-CoA is blocked? Decreases

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Where do most statins see their effects? Liver

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What is absorbed more when HMG-CoA is blocked? LDL

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When should statins best taken? Night

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How long does it take to see peak statin effects? Weeks

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Where are fats and cholesterol absorbed? Small Intestine

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