StudyGallery.com NSAIDs

Cyclooxygenase (COX) is an enzyme

COX converts prostaglandins into arachidonic acid

COX creates prostaglandins

There are two forms of COX

COX 1 protects the stomach lining

COX 1 regulates blood platelets

COX 2 triggers inflammation

COX 2 triggers pain

Aspirin blocks the formation of prostaglandins

Analgesic is pain relief

Aspirin
Blood clotting, Prostaglandins

Blood clotting
Platelet aggregation

COX-1
Platelet aggregation, Platelet aggregation, Stomach

COX-2
Inflammation, Pain

Histamines
Arterioles, Capillaries

Infection
Inflammation

NSAIDs
Prostaglandins, Stomach

Pain
COX-2

Prostaglandins
Smooth muscle, Stomach

What is Cyclooxygenase (COX)? Enzyme

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What does COX convert tiny prostaglandins into? Arachidonic acid

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What is created by COX? Prostaglandins

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How many different COX forms are there? Two

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Which COX protects the stomach lining? COX-1

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Which COX regulates blood platelets? COX-1

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What triggers inflammation? COX-2

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What triggers pain? COX-2

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What does aspirin block the formation of? Prostaglandins

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What is another term for pain relief? Analgesic

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What do NSAIDs inhibit? COX

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What is another term for NSAIDs? Prostaglandin Inhibitors

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What happens to fever and pain when COX-2 is inhibited? Decreases

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Do COX-2 inhibitors have an effect on the stomach? No

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What does COX-1 inhibitor decrease the lining to? Stomach

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What does COX-1 blocking decrease? Platelet aggregation

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What happens to platelet aggregation by blocking COX-2? Decreases

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What do prostaglandins help protect? Stomach

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What control prostaglandins? COX

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What do salicylates block the formation of? Prostaglandins

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What do salicylates block? Inflammation

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What do salicylates block? Fever

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What do salicylates block? Pain

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