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Pinch to Zoom Antiarrhythmic
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Class I has three subclasses. Ia, Ib, Ic Started with too many strong drinks and called a CAB. Class Ic for is most potent and Ib is weakest
Class Ic has the strong Sodium blocking
Class Ia moderately blocks Sodium channels
Class Ib has the weakest Sodium blockage
Class I interfere with the Sodium channel
Class I agents are grouped by their effect on the Na channel, and by their effect on cardiac action potentials
Class I stabilize the membrane of myocardial cells
Class Ib affect the Purkinje fibers. Class Ib only used for ventricular arrhythmias
4 antiarrhythmia classes I imagine Brad's heart racing before calculus so he smokes pot to calm down.
Antiarrhythmics target the heart Professor Johnny teaches the keyword is rhythm, like heart rhythm
The rhythm and rate needs to be right
Arrhythmias impact the automatic function or conductivity of heart cells Keyword is rhythm. Everything needs to be in sync for the heart to function
Four drug classes
Class I blocks sodium channels
Class II blocks beta receptors
Beta blockers decrease the rate the SA node fires, decreasing heart rate
Beta blockers treat supraventricular tachycardia
Beta blockers treat atrial fibrillation and atrial flutter
Class II decreases heart rate Beta 1 receptors stimulate the heart. Class II blocks beta receptors which would slow the heart
Class II impact the kidney
Class III blocks potassium channels
Class IV blocks calcium channels
*Class I, II, III, IV
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What is abnormal for an arrhythmia? Heart Rate
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What is abnormal for an arrhythmia? Heart Rhythm
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What do Class I block? Sodium So brad smoked pot before calculus. So for sodium in order of I, II, III, IV
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What do Class I help stabilize? Membrane
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What do Class II block? Beta Adrenergic Receptors so Brad smoked pot before calculus. Brad for Beta in order of I, II, III, IV
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What do Class II treat? Supraventricular Tachycardia
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What do Class II impact? Kidney Beta receptors are also on the kidneys
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What is decreased by Class II? Renin Release
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Which targets Beta receptors? Class II
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Which targets sodium? Class I
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What does Class III block? Potassium so brad smoked Pot before calculus. Pot for potassium in order of I, II, III, IV
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What does Class IV block? Calcium Ions so brad smoked pot before Calculus. Calculus for calcium in I, II, III, IV order
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