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Calcium causes contraction Form a "C" with your arm
Two hydro pyramid dams in California with lots of pine trees
Water from the 2 dams flows like blood vessels
Vera and Pam live in California with no pine trees or dams. They warm your heart
Used for hypertension, angina, and supraventricular arrhythmias
Most calcium channel blockers (end in -dipine) widen blood vessels
Calcium channel blockers have two main groups
Dihydropyridines target blood vessels (vascular smooth muscle) end in -dipine Water from dams flows like blood vessels. Di - hydro - pyr - idines
Non-dihydropyridines target the heart
Calcium channel blocker decreases heart contraction force
CCB block L-type calcium channels in the heart and the vascular smooth muscles
CCB decrease the calcium entering the cell during action potential
Slower pacemaker potential and slower depolarization
Extends phase 4 and phase 0 action potential, reducing SA node firing and heart rate
Decrease SA node firing
Decrease conduction velocity of AV node
*Calcium's role, Dihydropyridines, Non-dihydropyridines
Arteries
Blood Pressure
Calcium
Heart, Smooth muscle
Calcium channel blocker
Blood Pressure, Calcium
Heart
Blood Pressure
Smooth muscle
Arteries
What is another name for calcium channel blockers? Calcium Antagonist
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What reflex can calcium channel blockers cause? Tachycardia
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Which is the largest group of calcium channel blockers? Dihydropyridines
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What does a calcium channel blocker do to heart contraction force? Decrease
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What happens to arteries as a result of calcium channel blockers? Dilates
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What do Dihydropyridines target? Blood vessels Imagine vessels looking like rivers from a water dam
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What do Non-dihydropyridines target? Heart
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What do CCB do to phase 4 action potential? Extend
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