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Phenytoin is the most common drug for seizures
Phenytoin has a low toxicity
Phenytoin is believed to protect against seizures by causing voltage-dependent block of voltage gated sodium channels.
This blocks sustained high frequency repetitive firing of action potentials.
The primary site of action appears to be the motor cortex where spread of seizure activity is inhibited.
Carbamazepine is a sodium channel blocker
In the UK, both clobazam and clonazepam are second-line choices for treating many forms of epilepsy.
Diazepam is a Benzodiazepine sedative
Two medications at once is recommended only if a single medication does not work.
It usually takes a couple of weeks for carbamazepine to work.
Which activity do succinimides suppress? electrical
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What do benzodiazepines stabilize? nerve membranes
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What do hydantoins stabilize? nerve membranes
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Which describes hydatoins? Less Sedating
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What do hydantoins do to conduction? decrease
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What do hydantoins do to nerve membranes? Stabilize
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Which targets sodium channels? Hydantoin
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Which targets GABA? Benzodiazepines
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What do benzodiazepines do to GABA effects? Enhance
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How many drugs should be used when starting epilepsy treatment? Single
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What adjustment can be made to the dosage when beginning a new drug to see best results? Increased
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What is considered when deciding a medication? Type of seizure
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Which class does phenytoin belong to? Hydantoins
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How is phenytoin used for seizures? Both
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How should anticonvulsants be discontinued? Tapered
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How does Carbamazepine work? Sodium channel blocker
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What do Benzodiazepines do to brain activity? Depress
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How is diazepam usually used for seizures? Short term Tolerance can develop
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What does valproic or carboxylic acid target? Unknown
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Which is Oxcarbazepine similar to? carbamazepine
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Which does Topiramate possibly act on? Both
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Which family does Ethosuximide belong to? Succinimides
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Which type does Ethosuximide treat? Absence
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What do Sulfonamides target? Bacteria
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